o antigen การใช้
- There are over 170 O antigens, over 100 K antigens and over 50 H antigens.
- The first, O antigen, is a component of the lipopolysaccharide ( LPS ), of which 9 varieties exist.
- The role of O antigen changes in the establishment or maintenance of acute or chronic infection, if any, is unknown.
- Finally, the LPS O antigen content of " L . interrogans " differs in an acutely infected versus a chronically infected animal.
- This cross-protection by a typhoid vaccine is most likely due to O antigens shared between different " S . enterica " serotypes.
- Hence, when we refer to pathogenic strain O157 : H7, it means that this E . coli has O antigen 157 and H antigen 7.
- The chemical composition of these side chains both with respect to components and arrangement of the different sugars determines the nature of the somatic or O antigen determinants, which are essential means of serologically classifying many Gram-negative bacteria.
- Group I K antigens are only found with certain O-antigens ( O8, O9, O20, and O101 groups ), they are further subdivided on the basis of absence ( IA, similar to that of " Klebsiella " species in structure ) or presence ( IB ) of amino sugars and some group I K-antigens are attached to the lipid A-core of the lipopolysaccharide ( K LPS ), in a similar way to O antigens ( and being structurally identical to O antigens in some instances are only considered as K antigens when co-expressed with another authentic O antigen ).
- Group I K antigens are only found with certain O-antigens ( O8, O9, O20, and O101 groups ), they are further subdivided on the basis of absence ( IA, similar to that of " Klebsiella " species in structure ) or presence ( IB ) of amino sugars and some group I K-antigens are attached to the lipid A-core of the lipopolysaccharide ( K LPS ), in a similar way to O antigens ( and being structurally identical to O antigens in some instances are only considered as K antigens when co-expressed with another authentic O antigen ).
- Group I K antigens are only found with certain O-antigens ( O8, O9, O20, and O101 groups ), they are further subdivided on the basis of absence ( IA, similar to that of " Klebsiella " species in structure ) or presence ( IB ) of amino sugars and some group I K-antigens are attached to the lipid A-core of the lipopolysaccharide ( K LPS ), in a similar way to O antigens ( and being structurally identical to O antigens in some instances are only considered as K antigens when co-expressed with another authentic O antigen ).